The Deion Branch Charitable Foundation is a non-profit organization whose mission is to offer support to children's mental, physical, and emotional well-being by assisting programs and initiatives aimed at improving their quality of life.

Branch who established his foundation in 2002 after his son, Deiondre was diagnosed with Meningitis. He says, "I am very fortunate to be in a position to do this, I do this to honor my 7-year-old son, who is my strength. People tend to look at pro athletes as heroes, but to me, the heroes are Drs. Lakshmi Rajogopal and Amanda Jones, and the research staff at Children's who are working to prevent this terrible disease."